No articles match
Exposure-Response Model Assessing the Impact of Covariates on Probabilities of Clinical Outcome10 months ago
Simulating an Exposure Response Model using mrgsolve | Visualizing Probability of Cure | Adding Between Subject Variability on Intercept and Showing its Impact on Probabilities | Computing the Probabilities | Dose/Exposure Response Curves | Visualize the Response versus exposures (AUC)
Introduction to coveffectsplot10 months ago
Motivation | Example | Simulating Data to Mimick Outputs from a Modeling Exercise | Visualizing Covariate Effects with Distributions | Simplifying the Distributions into Ranges of Effects | Plotting the Effects Data
PK Model in Pediatric Patients: Assessing the Impact of a Multivariate Correlated Distribution of Covariates on PK Exposures10 months ago
Specifying A Pediatric Simulation Model | PK Parameters and Associated BSV ranges | Simulating Age/Weight Pairs Using NHANES LMS Values | Simulation with the Multivariate Realistic Distribution | PK Parameters Summaries and Distribution Plots | A Forest Plot with a Side Table
PK Model: Assessing the Marginal Impact of Covariates on Drug Exposure10 months ago
Specifying a PK Model using mrgsolve | Simulate a Reference Subjects with BSV | Compute PK Parameters, Plot and Summarize BSV | Generate and Simulate at Combinations of Covariate of Interest | Generate a Dataset Holding Combinations of Covariates: | Simulation at Unique Combinations of Covariates | Adding Uncertainty from a Varcov Matrix | Generating Sets of Parameters with Uncertainty | Iterative Simulations to Apply the Uncertainty | Compute PK Parameters and Boxplots | Alternative View of the Data: Distributions and Intervals | Adding the BSV Ranges and Putting it all Together Using forest_plot | Customization of the Plots | Using theme_benrich along Additional Options | Returning a List of ggplots | Plots with Multiple PK Parameters | Facet by Parameter | Shape by Parameter | Color by Parameter
PK Model: Assessing the Impact of Joint Covariates Distributions and BSV on Drug Exposure10 months ago
Specifying a PK Model using mrgsolve | Simulate a Reference Subjects with BSV | Compute PK Parameters, Plot and Summarize BSV | Importing Realistic Distributions of Covariates | Visualize the dataset of Covariates: | Simulation With Full Distributions of Covariates | Adding Uncertainty from a Varcov Matrix | Generating Sets of Parameters with Uncertainty | Iterative Simulation to Apply the Uncertainty | Compute PK Parameters and Boxplots | Alternative View of the Data: Distributions and Intervals | Putting it all Together Using forest_plot | Computing Geometric Mean Ratios (GMR) using a category as reference
Introduction to ggquickeda2 years ago
PK/PD Model: Assessing the Impact of Covariates on a Biomarker3 years ago
Specifying a PK/PD Model using mrgsolve | Simulate Reference Subjects with BSV | Compute PD Parameters and Summarize BSV | Construct ans Simulate at Combinations of Covariate of Interest | Compute PD Parameters and Distributions Plots | Summarize, add the BSV Ranges and Putting it all Together Using forest_plot
Shiny App4 years ago
Shiny App4 years ago
Visualizing Summary Data5 years ago
Published Data | Load the Data into the app | X/Y Mappings and Splitting Options | Facets Options | Ordering of Variables and Values | Remove Default Points and add a Point Interval | Setting Titles, Captions and Logging the X axis | Example of what is Possible with ggquickeda
Additional Plots and Stats with ggquickeda6 years ago
Multiple Y variables, recoding continuous variables to categories and Medina/PI: | Boxplots, Median/PI, Mean: | Continuous and categorical variables descriptive stats: | Univariate Plots: